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猪群免疫失败的原因,你找过吗?
作者:admin 来源:九江博美莱生物制品有限公司  更新时间:2017-10-19 点击量:1187 
给猪群接种疫苗,从而增强猪群对疾病的抵抗力,是当今养猪业有效控制猪病发生和传播的重要手段,但是有时候给猪群免疫疫苗了,猪群还是会发病,导致猪群免疫失败的原因有哪些呢?


一、猪群自身的角度

     猪群自身营养状况不好,体况差


  ZHUQUNZAIJINXINGYIMIAOMIANYIYIHOU,WULUNSHIYIMIAOCIJIDONGWUJITIDETIYEMIANYI、XIBAOMIANYIHAISHIZHANMOMIANYI,ZAIJITICHANSHENGKANGTIHEMOUXIEXIBAOYINZIDEGUOCHENGZHONG,DOUHUIYIDANBAIZHI、WEISHENGSU、ANJISUANDENGYINGYANGWUZHIZUOWEIJICHU,CISHI,RUGUOZHUQUNYINGYANGZHUANGKUANGBUHAO,TIKUANGJIAORUO,DOUHUIDAOZHIMIANYIFANYINGSHOUDAOMINGXIANYIZHI,CONGERDAOZHIYIMIAOMIANYIDESHIBAI。


  受母源抗体的影响


  MUYUANKANGTIDEYINGXIANGDAOZHIMIANYISHIBAI,SHIDAOZHIZHUQUNMIANYISHIBAIDECHANGJIANYUANYINZHIYI,GUANYUMUYUANKANGTIGANRAOYIMIAODEMIANYIXIAOGUO,ZHUYAOSHICONGXIBAOMIANYIHETIYEMIANYILIANGGEFANGMIANDUIYIMIAOMIANYICHANSHENGGANRAO,QIZHUYAODEZUOYONGJILISHIMUYUANKANGTIHUIJIASUKANGYUANWUZHIDEQINGCHU、DUIRUODUMIAOCHANSHENGZHONGHEZUOYONG、MUYUANKANGTIYUTEYIXINGKANGYUANWEIDIANDESHIBIEHEJIEHEZUZHILEKANGYUANWEIDIANYUJITIMIANYIXIBAOSHANGDEKANGYUANSHOUTIJIEHEERDAOZHIMIANYIXITONGBUNENGZUOCHUXIANGYINGDEMIANYIYINGDA。


  因此,选择合适的免疫时间,有效的避开母源抗体的干扰显得尤为重要。



二、药物的角度


  滥用抗生素


  LANYONGKANGSHENGSUDAOZHIMIANYISHIBAI,ZHUYAOSHIZHENDUIMOUXIERUODUJUNYIMIAO(ZIZHUFUSHANGHANHUOYIMIAOCVCC79500、ZHUDANDUHUOYIMIAOG4T10ZHU、ZHUBAIXUEXINGLIANQIUJUNBINGHUOYIMIAOST171ZHU),ZAIMIANYIQIANHUOZHEMIANYIHOULANYONGHUANGANLEIHEMOUXIEKANGJUNSULEIYAOWU,HUIDAOZHIHUOJUNSHIQUZUOYONG,BINGQIE,ZHEIXIEYAOWUYEHUIZAIYIDINGCHENGDUSHANGYIZHIBLINBAXIBAODEZENGZHI,SHIBAIXIBAOJIANSHAO,YINGXIANGMIANYIYINGDADESHUIPING,DAOZHIZHUQUNMIANYISHIBAI。


三、疾病感染的角度


  受某些免疫抑制性疾病的影响


  MUQIAN,ZHUQUNSHOUMOUXIEMIANYIYIZHIJIBINGDEYINGXIANG,CONGERDAOZHIMIANYIYINGDAGONGNENGSHOUDAOXIANZHI,YESHIDAOZHIZHUQUNMIANYISHIBAIDEZHONGYAOYUANYIN。ZAISHIJISHENGCHANZHONG,CHANGJIANDEZHUMIANYIYIZHIJIBINGYOUZHUYUANHUANBINGDUBING,ZHUFANZHIYUHUXIZHANGAIZONGHEZHENG(LANERBING)DENG,YINCI,ZAIMIANYISHIYAOZUOHAODUIZHUQUNYIBINGDESHISHIGENZONGGONGZUO。


  野毒或强毒株趁机入侵感染


  ZHUQUNZAIJIEZHONGYIMIAOYIHOU,DAOYIMIAOCHANSHENGMIANYIBAOHULI,HUIXUYAOYIDINGDESHIJIAN,ERZHEIDUANSHIJIANQIAQIAYESHIYIGEQIANZAIDEWEIXIANQI,ZHEIQIJIAN,YIDANYOUYEDURUQINGANRANHUOZHEZAICIWEIXIANQIGANRANQIANGDU,CHANGCHANGHUIDAOZHIZHUQUNJIBINGDEFASHENG,ZAOCHENGMIANYISHIBAI。


四、疫苗免疫的角度


  在潜伏期进行免疫接种


  RUGUODUIZHUQUNDEJIANKANGZHUANGKUANGGENZONGBUJISHIBULEJIE,ZAIJIBINGDEQIANFUQIJINXINGMIANYIJIEZHONG,YOUYUMIANYIYINGJIDEYINGXIANG,CISHIZHUQUNJITIDEDIKANGLIDENGYIJINGXIANGDUIJIANRUO,ZENGJIALEBINGYUANTIGANRANZENGZHIDEJIHUI,CISHIMIANYIWUYIHUIJIAJUJIBINGDEFASHENG,ZHUZHIDEBINGSILVYEHUISUIZHIZENGJIA。


  疫苗使用和保存不当


  YIMIAOZAIBAOCUNHESHIYONGGUOCHENGZHONGWUBIYAOANZHAOZHENGQUEDEFANGFAHEFANGSHIBAOCUN,SUIRANMOUXIEYIMIAOZHONGHANYOUDONGGANBAOHUJI,DANSHIZAISHIJIYINGYONGGUOCHENGZHONG,HAISHIYAOBIMIANFANFUDONGRONG,YINWEIFANFUDONGRONGHUIJIANGDIMOUXIEYIMIAODEXIAOJIA,CONGERDAOZHIYIMIAOBUNENGCHONGFENDEFAHUIZUOYONGHUOZHEZHIJIEDAOZHIMIANYISHIBAI。


  WEILEJIANSHAOYINGJIFANYING,ZUIDACHENGDUDIFAHUIYIMIAODEZUOYONG,JIANYIZAIMIANYIZHIQIANDUIYIMIAOJINXINGYUWENCHULI,ZHEIYANGJINENGYOULIYUYIMIAODEXISHOU,YOUNENGJIANSHAOYINGJI。


五、其他因素的影响


  人为免疫操作不当


  ZHUCHANGSIYANGGUANLIRENYUANSUZHIHESHOUYIRENYUANJISHUCANCHABUQI,MIANYIGUOCHENGZHONGZHUSHEBUWEIBUZHUNQUE、BUXIAODU、ZHUSHEZHENTOUBUANZHULINGXUANZEZHANGDU,BUGENGHUANZHENTOUYIZHENDAODI,PIXIA、PINEI、JIROUZHUSHEFENBUQINGDENGWENTIPUBIANCUNZAI,DAOZHIMIANYIHOUKANGTISHUIPINGBUZHENGQIHUOZHEBUHEGE,YIMIAOMIANYIHOUQIBUDAOLIANGHAODEMIANYIBAOHUZUOYONG,CONGERDAOZHIMIANYISHIBAI。



  先天性遗传因素影响


  DONGWUJITINENGFOUDUIJIEZHONGDEYIMIAOKANGYUANCHANSHENGMIANYIYINGDA,ZAIYIDINGCHENGDUSHANGQUJUEYUDONGWUZISHENYICHUANYINSUDEYINGXIANG,DONGWUPINZHONGFANDUO,LAIYUANFUZA,JISHISHITONGYIPINZHONGBUTONGGETIDUITONGYIYIMIAODEFANYINGYEHUIBUYIZHI。YOUQISHIZAIZHUQUNYANGZHIDEGUOCHENGZHONG,WEILEXUANZHONG,“JINQIN”FANZHIDENGXINGWEIDECHUXIAN,SHIDEMOUXIEYINXINGJIYINZAI“JINQIN”FANZHIHOUDOUBIAOXIANCHULEXIANXINGZHUANGKUANG,YIDINGCHENGDUSHANGDAOZHIDONGWUZISHENMIANYIQUEXIANDEFASHENG,CONGERDAOZHIMIANYIDESHIBAI。


       BOMEILAIJIANYI:ZHUAHAORICHANGSIYANGGUANLIFANGMIANDEGEGEXIJIE,HELISHIYONGYIMIAO,CAINENGBAOZHENGZHUQUNJIANKANG,BAOZHENGYANGZHUYEJIANKANGWENDINGDEFAZHAN。

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